Genomic sequencing and genetic medicines & therapeutics are helping transform health care in key areas with growing demand, including drug development, precision medicine, and more.
The cost of genomic sequencing has dropped from nearly USD$100mm per genome in 2002 to less than USD$1,000 in 2020. Adoption has continued to rise, as costs plummet.1
CURE provides global exposure to emerging areas within the Health Care sector, at the intersection of science and technology.
1 National Human Genome Research Institute, Nov 2021
Inception Date | 8 Nov 2018 |
Management Costs (% p.a.) | 0.45 |
Currency Hedged | No |
Domicile | Australia |
Legal Form | Managed Investment Scheme |
SMSF Eligible | Yes |
NAV/Unit (A$) | 41.18360000 |
Currency (NAV) | AUD |
Shares Outstanding | 884,012 |
AUM (A$) | 36,406,762.39 |
The Global X S&P Biotech ETF (CURE) seeks to invest in companies that potentially stand to benefit from further advances in the field of genomic science, such as companies involved in gene editing, genomic sequencing, genetic medicine/therapy, computational genomics, and biotechnology.
The Global X S&P Biotech ETF (CURE) seeks to provide investment results that correspond generally to the price and yield performance, before fees and expenses, of the S&P Biotechnology Select Industry Index.
Ticker | CURE |
Bloomberg Code | CURE AU Equity |
ISIN | AU0000028110 |
Trading Hours | 10:00AM – 4:00PM |
Issuer | Global X Management (AUS) Limited |
Custodian | The Hongkong and Shanghai Banking Corporation Limited, Sydney Branch |
Registrar | Computershare Investor Services Pty Limited |
Benchmark | S&P Biotechnology Select Industry Index |
Provider | S&P Indices |
Ticker | SPSIBIN |
12-Month Yield | 0.00% |
12-Month Franking Level | 0.00% |
Distribution Frequency | Annually |
Distribution History | View |
Total Return (Fund) | Total Return (Benchmark) | Tracking Difference | Tracking Error | |
---|---|---|---|---|
1 Month | 11.25% | 11.35% | -0.10% | 0.05% |
3 Months | -2.20% | -2.02% | -0.18% | 0.14% |
1 Year | -0.20% | 0.11% | -0.32% | 1.65% |
3 Year p.a. | -14.06% | -13.78% | -0.28% | 0.98% |
5 Year p.a. | 1.85% | 2.30% | -0.45% | 0.86% |
10 Year p.a. | -- | -- | -- | -- |
Since Inception p.a. | 0.57% | 0.99% | -0.42% | 0.86% |
Net Assets (%) | Name | SEDOL | Market Price (Local) | Shares Held | Market Value (A$) |
---|---|---|---|---|---|
2.27 | IMMUNOGEN INC | 2457864 | 29.21 | 18,649 | 827,051 |
1.93 | MIRATI THERAPEUT | BBPK0J0 | 56.49 | 8,210 | 704,142 |
1.85 | TG THERAPEUTICS | B828K63 | 15.72 | 28,180 | 672,572 |
1.84 | APELLIS PHARMACE | BYTQ6X1 | 62.73 | 7,041 | 670,587 |
1.69 | BLUEPRINT MEDICI | BWY52P3 | 73.98 | 5,484 | 615,966 |
1.60 | IMMUNOVANT INC | BJRFSB7 | 39.19 | 9,761 | 580,784 |
1.58 | CRISPR THERAPEUT | BDHF4K6 | 64.54 | 5,863 | 574,505 |
1.55 | BIOHAVEN LTD | BPLZ7S5 | 33.06 | 11,274 | 565,882 |
1.44 | IONIS PHARMACEUT | BDJ0LS6 | 48.69 | 7,105 | 525,230 |
1.42 | VIKING THERAPEUT | BQQG1V1 | 18.48 | 18,426 | 516,985 |
1.40 | BRIDGEBIO PHARMA | BK1KWG8 | 32.52 | 10,306 | 508,846 |
1.36 | KARUNA THERAPEUT | BJMLSD2 | 205.48 | 1,589 | 495,723 |
1.31 | IOVANCE BIOTHERA | BF0DMK7 | 6.40 | 49,208 | 478,147 |
1.31 | UNITED THERAPEUT | 2430412 | 241.65 | 1,301 | 477,320 |
1.31 | NEUROCRINE BIOSC | 2623911 | 117.28 | 2,679 | 477,026 |
1.31 | NATERA INC | BYQRG48 | 58.15 | 5,402 | 476,924 |
1.31 | SEAGEN INC | BLPK4D2 | 218.98 | 1,432 | 476,094 |
1.29 | MADRIGAL PHARMAC | BD59BS7 | 208.32 | 1,489 | 470,946 |
1.27 | VAXCYTE INC | BKPVGH6 | 56.67 | 5,389 | 463,668 |
1.27 | GILEAD SCIENCES | 2369174 | 79.02 | 3,852 | 462,135 |
1.27 | AMGEN INC | 2023607 | 269.12 | 1,129 | 461,302 |
1.27 | HALOZYME THERAPE | 2975098 | 39.95 | 7,603 | 461,155 |
1.26 | BIOMARIN PHARMAC | 2437071 | 92.94 | 3,246 | 458,033 |
1.26 | IRONWOOD PHARMAC | B3MZ6K5 | 10.48 | 28,747 | 457,403 |
1.25 | TWIST BIOSCIENCE | BGKG6G7 | 26.98 | 11,147 | 456,610 |
1.25 | VERTEX PHARM | 2931034 | 350.15 | 853 | 453,470 |
1.23 | REGENERON PHARM | 2730190 | 840.14 | 352 | 448,993 |
1.23 | BEAM THERAPEUTIC | BK6L288 | 26.40 | 11,186 | 448,357 |
1.22 | ARCELLX INC | BPCJ1Q2 | 56.22 | 5,222 | 445,731 |
1.22 | ABBVIE INC | B92SR70 | 149.28 | 1,965 | 445,358 |
1.21 | EXELIXIS INC | 2576941 | 22.00 | 13,242 | 442,305 |
1.15 | CYTOKINETICS INC | BBBSBJ5 | 34.10 | 8,119 | 420,341 |
1.15 | RECURSION PHAR-A | BM9FJ13 | 7.60 | 36,326 | 419,157 |
1.13 | SAGE THERAPEUTIC | BP4GNK9 | 20.01 | 13,549 | 411,623 |
1.13 | BIOGEN INC | 2455965 | 239.29 | 1,130 | 410,533 |
1.13 | CEREVEL THERAPEU | BMVMJ12 | 41.22 | 6,546 | 409,665 |
1.09 | ALKERMES PLC | B3P6D26 | 25.86 | 10,149 | 398,471 |
1.09 | AMICUS THERAPEUT | B19FQ48 | 11.22 | 23,292 | 396,776 |
1.05 | KRYSTAL BIOTECH | BD6JX35 | 106.86 | 2,360 | 382,889 |
1.05 | INSMED INC | 2614487 | 27.96 | 8,995 | 381,842 |
1.04 | INCYTE CORP | 2471950 | 54.70 | 4,576 | 380,031 |
1.03 | ALNYLAM PHARMACE | B00FWN1 | 170.04 | 1,454 | 375,371 |
1.02 | ULTRAGENYX PHARM | BJ62Z18 | 40.46 | 6,021 | 369,862 |
1.01 | EXACT SCIENCES | 2719951 | 64.72 | 3,738 | 367,302 |
0.99 | CATALYST PHARMAC | B1G7Q03 | 14.15 | 16,789 | 360,684 |
0.98 | PROTAGONIST THER | BDCBCD8 | 20.36 | 11,519 | 356,072 |
0.98 | ARROWHEAD PHARMA | BYQBFJ8 | 23.95 | 9,792 | 356,059 |
0.97 | ACADIA PHARMACEU | 2713317 | 20.98 | 11,069 | 352,581 |
0.95 | ROIVANT SCIENCES | BMW4NZ9 | 9.83 | 23,237 | 346,800 |
0.94 | INTELLIA THERAPE | BYZM6C2 | 29.02 | 7,731 | 340,626 |
0.93 | NUVALENT INC-A | BMVBZD3 | 70.66 | 3,147 | 337,610 |
0.91 | MODERNA INC | BGSXTS3 | 80.32 | 2,720 | 331,694 |
0.90 | CRINETICS PHARMA | BDD19F8 | 33.27 | 6,502 | 328,432 |
0.89 | SAREPTA THERAPEU | B8DPDT7 | 87.03 | 2,442 | 322,671 |
0.87 | DYNAVAX TECHNOLO | BRJZSK0 | 13.31 | 15,677 | 316,801 |
0.84 | ROCKET PHARMACEU | BDFKQ07 | 25.23 | 7,947 | 304,415 |
0.81 | RHYTHM PHARMACEU | BF2YWG4 | 36.49 | 5,355 | 296,673 |
0.79 | ARDELYX INC | BN89V40 | 5.23 | 36,108 | 286,715 |
0.78 | PROTHENA CORP PL | B91XRN2 | 36.08 | 5,160 | 282,658 |
0.78 | SPRINGWORKS THER | BGMGM89 | 31.50 | 5,907 | 282,503 |
0.77 | REVOLUTION MEDIC | BL71K91 | 24.59 | 7,463 | 278,623 |
0.76 | NOVAVAX INC | BJDQXG4 | 5.57 | 32,641 | 276,035 |
0.75 | PTC THERAPEUTICS | B17VCN9 | 26.39 | 6,786 | 271,893 |
0.75 | VERACYTE INC | BFTWZY0 | 25.62 | 6,988 | 271,817 |
0.71 | EDITAS MEDICINE | BZ8FPH3 | 10.51 | 16,299 | 260,081 |
0.71 | CELLDEX THERAPEU | BJLV8T9 | 31.43 | 5,420 | 258,636 |
0.69 | VIR BIOTECHNOLOG | BK4PZ38 | 9.62 | 17,276 | 252,327 |
0.65 | VIRIDIAN THERAPE | BMDH2B6 | 18.14 | 8,627 | 237,598 |
0.65 | SYNDAX PHARMACEU | BN7Q7R7 | 16.65 | 9,344 | 236,207 |
0.63 | ARCUS BIOSCIENCE | BDZT9Y9 | 15.77 | 9,629 | 230,546 |
0.63 | BIOCRYST PHARM | 2100362 | 5.69 | 26,570 | 229,535 |
0.62 | MIRUM PHARMACEUT | BJDX8Y8 | 32.86 | 4,514 | 225,203 |
0.58 | VERICEL CORP | BSBMN89 | 33.86 | 4,119 | 211,750 |
0.58 | DENALI THERAPEUT | BD2B4V0 | 18.37 | 7,543 | 210,377 |
0.55 | IDEAYA BIOSCIENC | BK0VHF6 | 30.89 | 4,246 | 199,133 |
0.54 | BIOMEA FUSION IN | BNKF6N0 | 16.89 | 7,690 | 197,197 |
0.54 | GERON CORP | 2370381 | 2.07 | 62,563 | 196,623 |
0.53 | MYRIAD GENETICS | 2614153 | 18.52 | 6,857 | 192,806 |
0.53 | DISC MEDICINE IN | BMGJZJ8 | 61.01 | 2,076 | 192,298 |
0.52 | MORPHIC HOLDING | BK8M4J4 | 27.17 | 4,575 | 188,724 |
0.52 | 89BIO INC | BK1K484 | 9.86 | 12,563 | 188,068 |
0.51 | BLUEBIRD BIO INC | BBFL7S1 | 2.86 | 42,886 | 186,220 |
0.50 | AKERO THERAPEUTI | BK7Y2V9 | 19.87 | 6,037 | 182,123 |
0.49 | VERVE THERAPEUTI | BNKGXX2 | 12.79 | 9,218 | 179,000 |
0.49 | RELAY THERAPEUTI | BN2R582 | 9.37 | 12,424 | 176,745 |
0.47 | KYMERA THERAPEUT | BMPRZV5 | 23.00 | 4,938 | 172,435 |
0.43 | ARCTURUS THERAPE | BKC9SX3 | 23.79 | 4,368 | 157,769 |
0.43 | POINT BIOPHARMA | BNKJ1S2 | 14.06 | 7,339 | 156,663 |
0.43 | TRAVERE THERAPEU | BLFGJD5 | 8.64 | 11,907 | 156,193 |
0.42 | MANNKIND CORP | BF081J4 | 3.58 | 28,144 | 152,973 |
0.41 | CAREDX INC | BP3YM74 | 9.81 | 10,041 | 149,552 |
0.40 | CARIBOU BIOSCIEN | BNYJR68 | 5.81 | 16,690 | 147,224 |
0.40 | AGIOS PHARMACEUT | BCBVTX1 | 22.05 | 4,395 | 147,134 |
0.40 | DAY ONE BIOPHARM | BLB0YH0 | 12.27 | 7,796 | 145,232 |
0.40 | INHIBRX INC | BK1MBC3 | 24.97 | 3,810 | 144,440 |
0.38 | UNIQURE NV | BJFSR88 | 7.17 | 12,854 | 139,830 |
0.36 | ZENTALIS PHARMAC | BMQ5T49 | 12.96 | 6,599 | 129,846 |
0.35 | REGENXBIO INC | BZ0G875 | 19.58 | 4,336 | 128,898 |
0.34 | KURA ONCOLOGY IN | BYZD465 | 10.81 | 7,638 | 125,358 |
0.34 | AVIDITY BIOSCIEN | BMWHPY1 | 7.54 | 10,862 | 124,344 |
0.33 | KINIKSA PHARMA-A | BD0MGM0 | 17.27 | 4,575 | 119,958 |
0.32 | ADMA BIOLOGICS I | B9NSBM2 | 3.71 | 20,572 | 115,877 |
0.31 | XENCOR INC | BGCYWN8 | 20.25 | 3,642 | 111,972 |
0.30 | ANAVEX LIFE SCIE | BYTYP72 | 7.96 | 8,905 | 107,620 |
0.28 | KEROS THERAPEUTI | BM7V485 | 35.65 | 1,912 | 103,489 |
0.28 | DECIPHERA PHARMA | BZ1LFB2 | 14.80 | 4,597 | 103,296 |
0.27 | COHERUS BIOSCIEN | BRK0149 | 2.22 | 28,820 | 97,139 |
0.27 | ALLOGENE THERAPE | BFZNYB7 | 2.47 | 25,820 | 96,827 |
0.26 | CABALETTA BIO IN | BK5MWR1 | 16.23 | 3,884 | 95,707 |
0.26 | VERA THERAPEUTIC | BL55460 | 13.70 | 4,487 | 93,330 |
0.25 | 4D MOLECULAR THE | BKLXFX5 | 14.94 | 4,051 | 91,888 |
0.25 | MIMEDX GROUP INC | B1Z3TW5 | 8.01 | 7,386 | 89,823 |
0.24 | RAPT THERAPEUTIC | BK5T6R0 | 17.48 | 3,227 | 85,642 |
0.23 | COGENT BIOSCIENC | BLR6XK8 | 8.64 | 6,307 | 82,734 |
0.21 | DYNE THERAPEUTIC | BN15WD1 | 11.18 | 4,586 | 77,843 |
0.19 | REPLIMUNE GROUP | BDDVW37 | 7.29 | 6,145 | 68,013 |
0.19 | SPDR S&P BIOTECH | B0Y90K2 | 79.32 | 560 | 67,440 |
0.17 | AGENUS INC | B58J3K4 | 0.75 | 55,286 | 62,660 |
0.17 | SANA BIOTECHNOLO | BMFJJ97 | 3.72 | 10,685 | 60,348 |
0.16 | ACELYRIN INC | BQPF874 | 6.83 | 5,715 | 59,263 |
0.16 | ALECTOR INC | BJ4LDC4 | 6.12 | 6,139 | 57,042 |
0.15 | PRIME MEDICINE I | BPBJFM7 | 8.50 | 4,239 | 54,705 |
0.14 | SERES THERAPEUTI | BYNQNP8 | 1.09 | 30,796 | 50,964 |
0.14 | ANAPTYSBIO INC | BDRW1L7 | 16.36 | 2,050 | 50,919 |
0.12 | ARCUTIS BIOTHERA | BKX9VD3 | 2.16 | 13,789 | 45,220 |
0.12 | AVID BIOSERVICES | BFMZ4W7 | 4.64 | 6,375 | 44,910 |
0.12 | NURIX THERAPEUTI | BMVLGP2 | 8.60 | 3,250 | 42,435 |
0.12 | ALDEYRA THERAPEU | BLD36T3 | 3.16 | 8,838 | 42,402 |
0.11 | ITEOS THERAPEUTI | BMWXFT4 | 9.84 | 2,800 | 41,831 |
0.11 | LYELL IMMUNOPHAR | BN6MB18 | 1.92 | 13,977 | 40,744 |
0.10 | SCILEX HOLDING C | BLKFRT9 | 1.10 | 21,910 | 36,592 |
0.02 | MURAL ONCOLOGY | BRJQ8L4 | 3.99 | 1,014 | 6,143 |
Sector | Weight (%) | |
---|---|---|
Health Care | 99.7 | |
None | 0.2 | |
Other/Cash | 0.1 |
Country | Weight (%) | |
---|---|---|
United States | 96.0 | |
Ireland | 1.9 | |
Switzerland | 1.6 | |
Netherlands | 0.4 | |
Other/Cash | 0.1 |
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